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Collagen Induction Therapy

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The percutaneous collagen induction therapy is based on the discovery that repeated puncturing of the skin’s surface with fine needles stimulates collagen production in the vicinity of linear and hypertrophic scars, as well as wrinkles, an observation made during the 1990s by two research groups (Camirand and Doucet 1997; Fernandes 2002). Using this principle as a basis, the South African plastic surgeon Dr. Fernandes developed a new treatment technique: Percutaneous Collagen Induction Therapy.
How does collagen induction therapy work?
The principle behind this therapy is to stimulate the skin’s natural ability to repair itself. In ‘Percutaneous Collagen Induction Therapy’ fine needle pricks on the damaged skin region are used to produce intradermal hemorrhages and activate wound healing mechanisms without damaging the epidermis in the process.
Posttraumatic regeneration of the skin with the formation of a new, natural subepidermal collagen and elastin network and a thicker epidermis can be induced with virtually no downtime.
Depending on the indication, a variety of needle lengths can be used, extending to just below the stratum corneum (“micro-needling” or “Cosmetic Needling”), into the papillary dermis (“Medical Needling”) or even as far as the reticular dermis or subcutis (“Surgical Needling”)
What are the advantages of this therapy?
There are so many benefits of collagen induction therapy. Percutaneous collagen induction therapy helps in the reduction of fine lines over the face along with the reduction of sagging skin. This in turn translates into improved appearance of wrinkles and acne scars and skin tone.
Mesotherapy can be combined with micro-needling to maximize clinical outcomes. PRP can be used for skin rejuvenation along with micro-needling. There are various meso solutions available commercially for the reduction of black spots, wrinkles, scars, etc.
Details of technology:
Dermaroller: It is a simple handheld drum-shaped roller consisting of a handle with a cylinder studded with 192 fine stainless steel microneedles all around in eight rows 0.5-1.5mm in length and 0.1 mm in diameter. The microneedles are synthesized by reactive ion etching techniques on silicon or medical grade stainless steel.
The quality, hardness and sharpness of needles are important properties of a good skin needling device. The depth of neocollagenesis was found to be average 5 – 600 micrometers with a 1.5 mm length needle. It is pre-sterilised by gamma irradiation . Medical grade stainless steel makes the needles non- allergenic to human tissue. Re-sterilization of the dermaroller in an autoclave or using ultrasound is prohibited because needles would lose their sharpness and may detach from the roller.
Meso Pen: electronic micro-needling
The Meso Pen is an electronic transdermal penetration device that has the shape of a pencil or pen.
At one end it has a head with microneedles. This part is applied to the skin during treatment. We can adjust the depth of the needles and the speed of operation according to the type of skin, the area and the objectives of the treatment.
The Meso Pen opens more than 1,000 micro-channels per second in the skin and it is through these ducts where the active ingredients penetrate (hyaluronic acid, vitamins, minerals, peptides, amino acids, etc.). In addition, these micro-channels or skin micro-traumatisms cause an innate response of the body to repair the skin, resulting in the creation of collagen and elastin, among other benefits.
Which other body areas can be treated with this therapy?
This revolutionary collagen rejuvenation therapy can be used for face, neck, hands, abdomen, arms and legs.
How often do I need treatments?
For best results our doctors recommend 4-6 sessions at least 4 weeks apart. For severe acne, dark spots or pigmentation problems more sessions may be required.




Are there any risks or complications?
Even with the deep treatments, the risk of complications is extremely low. The columns of epidermal cells are mainly forced apart by the needles but are not significantly injured or even removed. The epidermis can close up fully within the first 24 hours after the procedure, minimizing the risk of infections and wound healing problems. While swellings, reddening, and bruising can develop in the treatment region (depending on needle length) for a few days in the course of the desired inflammation, these usually abate without any complications and without scarring. Furthermore, no post-inflammatory pigment changes are observed after the treatment, which is why needling can also be safely used in darker skin types.


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